Invitrogen™ RPAIN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520326

Catalog No. PIPA520326

Description

A suggested positive control is Jurkat cell lysate. PA5-20326 can be used with blocking peptide PEP-0446.

Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

Specifications

• Antigen: RPAIN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPAIN
• Gene Alias: 2400006N03Rik; hRIP; nuclear transporter; RAP interaction protein; RAP interaction protein alpha; RGD1308492; RIP; RPA interacting protein; RPA interacting protein delta 2; RPA interacting protein epsilon; RPAIN; RPA-interacting protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 287463, 69723, 84268
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q4G2Y1, Q86UA6, Q9CWY9
• Gene Symbols: RPAIN
• Immunogen: A 17 amino acid peptide from near the carboxy terminus of human RPA IP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG