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Invitrogen™ RPE65 Recombinant Rabbit Monoclonal Antibody (HL1519)
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Catalog No. PIMA547075
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100 μL
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PIMA547075 100 μL
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Catalog No. PIMA547075 Supplier Invitrogen™ Supplier No. MA547075
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Description

Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

RPE65 is a major protein of the retinal pigment epithelium (RPE). RPE65 is essential for the regeneration of rhodopsin in the visual cycle. Mutations in RPE65 are responsible for certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA). Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and the accumulation of retinyl esters in the RPE.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RPE65
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone HL1519
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene RPE65
Gene Accession No. Q16518, Q91ZQ5
Gene Alias 65kDa; A930029L06Rik; all-trans-retinyl-palmitate hydrolase; BCO family, member 3; BCO3; LCA2; Lutein isomerase; membrane receptor p63; meso-zeaxanthin isomerase; modifier of retinal degeneration 1; Mord1; mRPE65; p63; RBP-binding membrane protein; rd12; retinal pigment epithelium 65; retinal pigment epithelium 65-like; retinal pigment epithelium abundant protein RPE65; retinal pigment epithelium specific protein 65; retinal pigment epithelium, 65 kDa; retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific 65kD protein; retinal pigment epithelium-specific protein (65kD); retinal pigment epithelium-specific protein 65kDa; retinal pigment epithelium-specific protein RPE65; Retinitis pigmentos; retinitis pigmentosa 20 (autosomal recessive); retinoid isomerohydrolase; retinoid isomerohydrolase RPE65; retinol isomerase; RP20; RPE65; rpe65 gene for retinal pigment epithelium-specific protein; RPE65, retinoid isomerohydrolase; sRPE65; truncated RPE65
Gene Symbols RPE65
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human RPE65. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19892, 6121
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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