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RPE65 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989175
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100 μL
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50-198-9175 100 μL
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Catalog No. 50-198-9175 Supplier Bioss Supplier No. BS9575R
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Description

Rabbit Polyclonal Antibody

RPE65 is a major protein of the retinal pigment epithelium (RPE). RPE65 is essential for the regeneration of rhodopsin in the visual cycle. Mutations in RPE65 are responsible for certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA). Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and the accumulation of retinyl esters in the RPE.

Specifications

Antigen RPE65
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RPE65
Gene Accession No. Q16518
Gene Alias 65kDa; A930029L06Rik; All-trans-retinyl-palmitate hydrolase; BCO family, member 3; BCO3; BOS_3433; LCA2; Lutein isomerase; Meso-zeaxanthin isomerase; modifier of retinal degeneration 1; Mord1; mRPE65; p63; RBP-binding membrane protein; rd12; retinal pigment epithelium 65; retinal pigment epithelium 65-like; retinal pigment epithelium abundant protein RPE65; retinal pigment epithelium specific protein 65; retinal pigment epithelium, 65 kDa; Retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific protein (65kD); retinal pigment epithelium-specific protein 65kDa; Retinitis pigmentos; retinitis pigmentosa 20 (autosomal recessive); Retinoid isomerohydrolase; Retinol isomerase; RP20; Rpe65; rpe65 gene for retinal pigment epithelium-specific protein; RPE65, retinoid isomerohydrolase; sRPE65; truncated RPE65
Gene Symbols RPE65
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RPE65.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6121
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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