Invitrogen™ RPGR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102497

Catalog No. PIPA5102497

Description

Antibody detects endogenous levels of total RPGR.

This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

Specifications

• Antigen: RPGR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPGR
• Gene Alias: COD1; CORDX1; CRD; mRpgr; orf15; PCDX; retinitis pigmentosa 15; retinitis pigmentosa 3 GTPase regulator; retinitis pigmentosa GTPase regulator; RP15; RP3; Rp3h; Rpgr; X-linked retinitis pigmentosa GTPase regulator; XLRP3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19893, 367733, 6103
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q92834, Q9R0X5
• Gene Symbols: RPGR
• Immunogen: A synthesized peptide derived from human RPGR(Accession Q92834), corresponding to amino acid residues L974-L1020.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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