RPGR Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA567290

Catalog No. PIPA567290

Description

Immunogen sequence: PFFGNLPDRGM NTESEENKDF VKKRESCKQD VIFDSERESV EKPDSYMEGA SESQQGIADG FQQPEAIEFS SGEKEDDEVE TDQNIRYGRK LIEQG Highest antigen sequence identity to the following orthologs - mouse 48%, rat 29%.

This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

Specifications

• Antigen: RPGR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPGR
• Gene Alias: X-linked retinitis pigmentosa GTPase regulator; RPGR; RP3; XLRP3; CRD; COD1; PCDX; RP15; orf15; CORDX1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6103
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92834
• Gene Symbols: RPGR
• Immunogen: Recombit Human RPGR
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

For Research Use Only