Invitrogen™ RPL22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585680

Catalog No. PIPA585680

Description

Keep as concentrated solution. Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (95%), Xenopus laevis (92%), Pig (99%), Chicken (96%), Rhesus Monkey (99%). Positive Control: HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36. 3-p36. 2.

Specifications

• Antigen: RPL22
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPL22
• Gene Alias: 2700038K18Rik; 60S ribosomal protein L22; EAP; EBER-associated protein; Epstein-Barr virus small RNA-associated protein; Epstein-Barr-encoded RNA-associated protein; HBP15; HBP15/L22; heparin-binding protein 15; heparin-binding protein HBp15; hypothetical protein LOC557397; L22; Large ribosomal subunit protein eL22; ribosomal protein L22; RPL22; zgc:123327
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6146, 81768
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.92 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P35268, P47198
• Gene Symbols: RPL22
• Immunogen: Full length human RPL22 Recombinant protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG