RPL6 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA530217

Catalog No. PIPA530217

Description

Recommended positive controls: A549, H1299, HCT116, MCF-7. Predicted reactivity: Mouse (91%), Rat (91%), Xenopus laevis (81%), Pig (94%), Chicken (83%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: RPL6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPL6
• Gene Alias: 60S ribosomal protein L6; DNA-binding protein TAXREB107; L6; Large ribosomal subunit protein eL6; Neoplasm-related protein C140; ribosomal protein L6; Rpl6; SHUJUN-2; Taxreb107; TAX-responsive enhancer element-binding protein 107; TXREB1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117042, 19988, 6128
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P21533, P47911, Q02878
• Gene Symbols: RPL6
• Immunogen: Recombinant fragment corresponding to a region within amino acids 7 and 223 of Human RPL6
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov