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Invitrogen™ RPP30 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA576399
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.
Specifications
RPP30 | |
Polyclonal | |
Unconjugated | |
RPP30 | |
Ribonuclease P protein subunit p30; ribonuclease P/MRP 30 subunit; ribonuclease P/MRP 30kDa subunit; ribonuclease P/MRP subunit; ribonuclease P/MRP subunit p30; ribonuclease P2; RNase P subunit 2; RNaseP protein p30; RNASEP2; RPP30; TSG15 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
10556, 54364, 685332 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
O88796, P78346 | |
RPP30 | |
Recombinant fusion protein of human RPP30. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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