Invitrogen™ RPP30 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597075

Catalog No. PIPA597075

Description

Immunogen sequence: MAVFADLDLR AGSDLKALRG LVETAAHLGY SVVAINHIVD FKEKKQEIEK PVAVSELFTT LPIVQGKSRP IKILTRLTII VSDPSHCNVL RATSSRARLY DVVAVFPKTE KLFHIACTHL DVDLVCITVT EKLPFYFKRP PINVAIDRGL AFELVYSPAI KDSTMRRYTI SSALNLMQIC KGKNVIISSA AERPLEIRGP YDVANLGLLF GLSESDAKAA VSTNCRAALL HGETRKTAFG IISTVKKPRP SEGDEDCLPA SKKAKCEG; Positive Samples: HeLa, Jurkat, HT-1080, HepG2; Cellular Location: Nucleus, nucleolus.

RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.

Specifications

• Antigen: RPP30
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPP30
• Gene Alias: Ribonuclease P protein subunit p30; ribonuclease P/MRP 30 subunit; ribonuclease P/MRP 30kDa subunit; ribonuclease P/MRP subunit; ribonuclease P/MRP subunit p30; ribonuclease P2; RNase P subunit 2; RNaseP protein p30; RNASEP2; RPP30; TSG15
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10556, 54364, 685332
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.72 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O88796, P78346
• Gene Symbols: RPP30
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human RPP30 (NP_0064041).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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