Invitrogen™ RPP30 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531009

Catalog No. PIPA531009

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (89%), Rat (90%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.

Specifications

• Antigen: RPP30
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPP30
• Gene Alias: Ribonuclease P protein subunit p30; ribonuclease P/MRP 30 subunit; ribonuclease P/MRP 30kDa subunit; ribonuclease P/MRP subunit; ribonuclease P/MRP subunit p30; ribonuclease P2; RNase P subunit 2; RNaseP protein p30; RNASEP2; RPP30; TSG15
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10556
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.57 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P78346
• Gene Symbols: RPP30
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 268 of Human RPP30.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov