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Invitrogen™ RPRD1B Monoclonal Antibody (OTI1C7)
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Catalog No. PIMA526349
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100 μL
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PIMA526349 100 μL
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Catalog No. PIMA526349 Supplier Invitrogen™ Supplier No. MA526349
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Description

Mouse Monoclonal Antibody

RPRD1B Monoclonal Antibody for Western Blot, IHC (P)

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RPRD1B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1C7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RPRD1B
Gene Accession No. Q9NQG5
Gene Alias 2610304G08Rik; 2810446G03Rik; C20orf77; Cell cycle-related and expression-elevated protein in tumor; cell-cycle related and expression-elevated protein in tumor; CREPT; dJ1057B20.2; NET60; regulation of nuclear pre-mRNA domain containing 1B; regulation of nuclear pre-mRNA domain-containing protein 1B; RGD1304782; Rprd1b
Gene Symbols RPRD1B
Host Species Mouse
Immunogen Full length human recombinant protein of RPRD1B produced in HEK293T cell.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58490
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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