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Invitrogen™ RPS10 Polyclonal Antibody
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Catalog No. PIPA561484
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100 μL
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PIPA561484 100 μL
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Catalog No. PIPA561484 Supplier Invitrogen™ Supplier No. PA561484
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Rabbit Polyclonal Antibody

Immunogen sequence: GVMVAKKDVH MPKHPELADK NVPNLHVMKA MQSLKSRGCV KEQF Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S10 (RPS10) is a 165 amino acid component of the small ribosomal 40S subunit. While generally found in the cytoplasm, RPS10 can localize to the granular component (GC) region of the nucleolus. For this to occur, methylation by PRMT5 is required as well as an interaction with NPS1. Defects in RPS10 are the cause of Diamond-Blackfan anemia type 9 (DBA9). It is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RPS10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Rps10
Gene Accession No. P46783
Gene Alias 2210402A09Rik; 40S ribosomal protein S10; DBA9; ribosomal protein S10; RP11-375E1__A.4; Rps10; S10; Small ribosomal subunit protein eS10
Gene Symbols Rps10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RPS10.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6204
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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