RPS24 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9761	150 μL

Catalog No. 50-172-9761 Supplier Proteintech Group Inc Supplier No. 148311AP150UL

Description

Rabbit Polyclonal Antibody

Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintece. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at ′Ser-62′ and ′Ser-67′, respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro; however such activity is unsure in vivo. May be involved in megakaryocyte differentiation. Ota T., Nat. Genet. 36:40-45(2004). Deloukas P., Nature 429:375-381(2004). Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).

Specifications

• Antigen: RPS24
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.18 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: RPS24
• Gene Accession No.: P62847, P62849, P62850
• Gene Alias: 40S ribosomal protein S24, DBA3, ribosomal protein S24, RPS24
• Gene Symbols: RPS24
• Host Species: Rabbit
• Immunogen: RPS24 Fusion Protein Ag6621
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 20088, 6229, 81776
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG