Invitrogen™ Human RPS6KA1 (RSK1), His Tag Recombinant Protein

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

RPS6KA1 (RSK1) is a growth-factor regulated serine/threonine kinase that is involved in the MAPK cascade. It is thought to control cellular proliferation and differentiation through the phosphorylation of transcription factors. RPS6KA1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Accession Number: Q15418
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 6195
• Molecular Weight (g/mol): 88.5 kDa
• Name: Human RPS6KA1 (RSK1), His Tag
• Quantity: 10 μg
• Regulatory Status: For research use only. Not for use in diagnostic procedures
• Gene Alias: 90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90 kD, polypeptide 1); hu-1; MAP kinase-activated protein kinase 1; MAP kinase-activated protein kinase 1 A; MAPK-activated protein kinase 1; MAPK-activated protein kinase 1 A; MAPKAP kinase 1; MAPKAP kinase 1 A; MAPKAPK-1; mapkapk1a; MAPKAPK-1 A; p90Rsk; P90-RSK; p90-RSK 1; p90Rsk1; p90-Rsk1; p90S6K; pp90RSK1; ribosomal protein S6 kinase 2 alpha; ribosomal protein S6 kinase 2 beta; ribosomal protein S6 kinase a, polypeptide 1; ribosomal protein S6 kinase A1; ribosomal protein S6 kinase A1 L homeolog; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase II alpha; ribosomal protein S6 kinase II beta; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90 kD, polypeptide 1; Ribosomal protein S6 kinase, 90 kD, 1; ribosomal protein S6 kinase, 90 kDa, polypeptide 1; ribosomal protein S6 kinase, 90 kDa, polypeptide 1 L homeolog; ribosomal protein S6 kinase, polypeptide A1; ribosomal S6 kinase 1; RPS6KA; Rps6ka1; rps6ka1.L; RPS6KA1L; rsk; RSK1; Rsk-1; S6 kinase II beta; S6 protein kinase (Rsk-1); S6K-alpha 1; S6K-alpha-1; S6KII-alpha; S6KII-beta; wu:fc56h07; XELAEV_18012109mg; zgc:152654
• Common Name: RSK1
• KinaseFamily: RSK (RPS6K) Kinase family
• Product Type: RPS6KA1 (RSK1) Recombinant Human Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Expression System: Insect cells
• Protein Family: Kinases and inhibitors
• Form: Liquid
• Protein Subtype: Serine/threonine kinase