Invitrogen™ RPS6KB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590447

Catalog No. PIPA590447

Description

Immunogen sequence: MAAVFDLDLE TEEGSEGEGE PELSPADACP LAELRAAGLE PVGHYEEVEL TETSVNVGPE RIGPHCFELL RVLGKGGYGK VFQVRKVQGT NLGKIYAMKV LRKAKIVRNA KDTAHTRAER NILESVKHPF IVELAYAFQT GGKLYLILEC LSGGELFTHL EREGIFLEDT; Positive Samples: HeLa, SH-SY5Y, HL-60, SW620, MCF7, Mouse liver, Mouse kidney, Mouse spleen, Rat liver; Cellular Location: Cytoplasm, Nucleus.

RPS6KB2 (p70S6K beta) is a serine/threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Specifications

• Antigen: RPS6KB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rps6kb2
• Gene Alias: 70 kDa ribosomal protein S6 kinase 2; 70kDa; KLS; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6KB; p70 S6K-beta; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70-S6K 2; P70S6K2; p70S6Kb; ribosomal protein S6 kinase B2; ribosomal protein S6 kinase beta-2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; ribosomal protein S6 kinase, polypeptide 2; RPS6KB2; S6 kinase 2; S6 kinase-related kinase; S6K2; S6K-beta; S6K-beta2; S6K-beta-2; serine/threonine-protein kinase 14 beta; serine/threonine-protein kinase 14B; SRK; STK14B
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 361696, 58988, 6199
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UBS0, Q9Z1M4
• Gene Symbols: Rps6kb2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human p70 S6 Kinase 2 (NP_0039432).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov