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Invitrogen™ RRAD Polyclonal Antibody
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Catalog No. PIPA5101621
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100 μL
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PIPA5101621 100 μL
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Catalog No. PIPA5101621 Supplier Invitrogen™ Supplier No. PA5101621
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RAD.

The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RRAD
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RRAD
Gene Accession No. P55042
Gene Alias GTP-binding protein RAD; RAD; RAD1; RAS (RAD and GEM) like GTP binding 3; ras associated with diabetes; Ras-like GTP-binding protein rad; Ras-related associated with diabetes; REM3; RRAD; RRAD, Ras related glycolysis inhibitor and calcium channel regulator; RRAD, Ras related glycolysis inihibitor and calcium channel regulator
Gene Symbols RRAD
Host Species Rabbit
Immunogen A synthesized peptide derived from human RRAD(Accession P55042), corresponding to amino acid residues A49-A99.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6236
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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