Invitrogen™ RRAGC Polyclonal Antibody

Catalog No.	Quantity
PIPA517017	100 μL

Catalog No. PIPA517017 Supplier Invitrogen™ Supplier No. PA517017

Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

RRAGC (Ras-related GTP-binding protein C) is a monomeric guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulations of the mTORC1 signaling cascade. RRAGC forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. It cycles between an inactive GTP-bound and an active GDP-bound form. RRAGC, in its active form, participates in the re-localization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This re-localization is a crucial step in the activation of the TOR signaling cascade by amino acids.

Specifications

• Antigen: RRAGC
• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 19 μg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene: Rragc
• Gene Accession No.: Q99K70, Q9HB90
• Gene Alias: AU041672; GTPase-interacting protein 2; GTR2; Rag C; Rag C protein; RAGC; Ras related GTP binding C; Ras-related GTP binding C; ras-related GTP-binding protein C; RRAGC; small GTPase homolog; small GTPase, homolog; TIB929; YGR163W
• Gene Symbols: Rragc
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to the sequence of human RagC protein.
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 298514, 54170, 64121
• Target Species: Human, Mouse, Rat, Monkey
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov