Invitrogen™ RRAS2 Monoclonal Antibody (EM-50), PE

Catalog No.	Quantity
PIMA528615	100 μg

Catalog No. PIMA528615 Supplier Invitrogen™ Supplier No. MA528615

Description

Mouse Monoclonal Antibody

This antibody recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.

RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTP binding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.

Specifications

• Antigen: RRAS2
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: EM-50
• Concentration: 0.1 mg/mL
• Conjugate: PE
• Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Gene: RRAS2
• Gene Accession No.: P62070
• Gene Alias: 2610016H24Rik; C86394; Ras-like protein TC21; ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2; Rras2; TC21; Teratocarcinoma oncogene
• Gene Symbols: RRAS2
• Host Species: Mouse
• Immunogen: Human TC21.
• Purification Method: Size-exclusion chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22800
• Target Species: Human
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ