Invitrogen™ RRAS2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5104087	100 μL

Catalog No. PIPA5104087 Supplier Invitrogen™ Supplier No. PA5104087

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RRAS2.

RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTP binding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.

Specifications

• Antigen: RRAS2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: RRAS2
• Gene Accession No.: P62070, P62071
• Gene Alias: 2610016H24Rik; C86394; Ras-like protein TC21; ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2; Rras2; TC21; Teratocarcinoma oncogene
• Gene Symbols: RRAS2
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human RRAS2(Accession P62070), corresponding to amino acid residues V164-F204.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22800, 365355, 66922
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov