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Invitrogen™ RRAS2 Polyclonal Antibody
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Catalog No. PIPA5121063
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100 μL
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PIPA5121063 100 μL
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Catalog No. PIPA5121063 Supplier Invitrogen™ Supplier No. PA5121063
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HT-29, SKOV3, NIH/3T3, Mouse kidney, Mouse heart, Mouse lung, Rat kidney. The target is usually found in the following locations: Cell membrane, Cytoplasmic side, Lipid-anchor. Immunogen sequence: MAAAGWRDGS GQEKYRLVVV GGGGVGKSAL TIQFIQSYFV TDYDPTIEDS YTKQCVIDDR AARLDILDTA GQEEFGAMRE QYMRTGEGFL LVFSVTDRGS FEEIYKFQRQ ILRVKDRDEF PMILIGNKAD LDHQRQVTQE EGQQLARQLK VTYMEASAKI RMNVDQAFHE LVRVIRKFQE QECPPSPEPT RKEKDKKGCH CVIF.

RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTP binding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RRAS2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RRAS2
Gene Accession No. P62070, P62071
Gene Alias 2610016H24Rik; C86394; Ras-like protein TC21; ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2; Rras2; TC21; Teratocarcinoma oncogene
Gene Symbols RRAS2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-204A of human RRAS2 (NP_036382.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22800, 365355, 66922
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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