Invitrogen™ RRM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588145

Catalog No. PIPA588145

Description

Immunogen sequence: IRNSLLIAPM PTASTAQILG NNESIEPYTS NIYTRRVLSG EFQIVNPHLL KDLTERGLWH EEMKNQIIAC NGSIQSIPEI PDDLKQLYKT VWEISQKTVL KMAAERGAFI DQSQSLNIHI AEPNYGKLTS MHFYGWKQGL KTGMYYLRTR PAANPIQFTL NKEKLKDKEK VSKEEEEKER NTAAMVCSLE NRDECLMCGS; Positive Samples: HeLa, MCF7, HT-29, A-549, SW620, Mouse testis, Mouse spleen, Mouse thymus; Cellular Location: Cytoplasm.

RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is involved in carcinogenesis, tumor progression.

Specifications

• Antigen: RRM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RRM1
• Gene Alias: cb396; cb838; CHUNP6866; hypothetical protein; R RRM 1; r1; RI RI RR 1; Ribonucleoside-diphosphate reductase large subunit; ribonucleoside-diphosphate reductase M1 chain; ribonucleoside-diphosphate reductase subunit M1; ribonucleotide reductase catalytic subunit M1; ribonucleotide reductase large subunit; ribonucleotide reductase M1; ribonucleotide reductase M1 L homeolog; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase M1 S homeolog; ribonucleotide reductase protein R1 class I; ribonucleotide reductase subunit M1; ribonucleotide reductase, R1 subunit; RIR 1; RIR1; RnrM1; RR1; Rrm1; rrm1 protein; rrm1.L; rrm1.S; sb:cb548; wu:fb39b07; wu:fi14b02; wu:fk95f07; XELAEV_18013932mg; XRRM1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20133, 6240, 685579
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P07742, P23921
• Gene Symbols: RRM1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_0010241).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov