Invitrogen™ rRNA Monoclonal Antibody (Y10b), HRP

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA516063

Catalog No. PIMA516063

Description

rRNA Monoclonal Antibody for IHC (P)

rRNA (ribosomal RNA) forms a major structural component of ribosomes which provides a mechanism for decoding mRNA information into amino acids/proteins through the process of translation. rRNA plays a key role in accurate positioning of mRNA as well as peptidyl tRNA, and also plays a structural role in peptidyl transferase activity by generating scaffolds where ribosomal proteins are assembled. rRNA is generated inside nucleolus, which is localized in nucleus of the cells and contains genes essential for encoding rRNA. Defective rRNA may implicate in certain pathologies, for example: decreased rRNA expression has been observed in subjects with myelodysplastic syndromes, and abnormal rRNA expression has also been linked to Alzheimer's disease.

Specifications

• Antigen: rRNA
• Classification: Monoclonal
• Concentration: 0.77 mg/mL
• Formulation: PBS with no preservative
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: All species
• Product Type: Antibody
• Isotype: IgG3 κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: Y10b
• Conjugate: HRP
• Gene Alias: ribosomal RNA; rRNA
• Immunogen: The whole 5.8S ribosomal RNA.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: 4°C, store in dark
• Form: Liquid