RSAD2 Mouse anti-Human, Clone: OTI4D12, liquid, TrueMAB™

Catalog No.	Quantity
50-167-6214	100 μL

Catalog No. 50-167-6214 Supplier OriGene Supplier No. TA505799

Description

Mouse Monoclonal Antibody

Viperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins. Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways. Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006). Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011). Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, ). Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies.

Specifications

• Antigen: RSAD2
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI4D12
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: RSAD2
• Gene Accession No.: Q8WXG1
• Gene Alias: 2510004L01Rik, cig33, cig5, vig1
• Gene Symbols: RSAD2
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human RSAD2 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 91543
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b