RSAD2 Mouse anti-Human, Clone: OTI4D12, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA505799
DescriptionViperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins. Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways. Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006). Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011). Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, ). Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|2510004L01Rik, cig33, cig5, vig1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Full length human recombit protein of human RSAD2 produced in HEK293T cell.|
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