Invitrogen™ RSPH4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556666

Catalog No. PIPA556666

Description

Immunogen sequence: RPWEGKTAAS PQYSEPESSE PLEAKQGPET GRQSRSSRPW SPQSRAKTPL GGPAGPETSS PAPVSPREPS SSP Highest antigen sequence identity to the following orthologs: Mouse - 41%, Rat - 37%.

This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: RSPH4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RSPH4A
• Gene Alias: A230081C05; CILD11; dJ412I7.1; radial spoke head 4 homolog A; radial spoke head 4 homolog A (Chlamydomonas); radial spoke head protein 4 homolog A; Radial spoke head-like protein 3; radial spokehead-like 3; RSHL3; Rsph4a; RSPH6B
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 345895
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5TD94
• Gene Symbols: RSPH4A
• Immunogen: Recombinant protein corresponding to Human RSPH4A. Recombinant protein control fragment (Product #RP-94636).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG