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RSPO1 Mouse anti-Human, Clone: OTI1C3, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF804766

Catalog No. 50-166-7127


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

RSPO1 is a member of a family of secreted growth factors that can operate through the canonical Wnt signaling pathway by stabilizing the intracellular beta-catenin, thereby regulating functions mediated by beta-catenin such as cell fate decisions and embryonic patterning. RSPO1 was recently identified through linkage analysis to be involved in sex determination and mammalian ovarian development. RSPO1 is thought to regulate cellular responsiveness to Wnt ligands by modulating the cell-surface expression of the Wnt co-receptor LRP6 by interfering with the DKK/Kremen-mediated internalization of LRP6 through an interaction with Kremen, resulting in increased LRP6 cell-surface levels. At least two isoforms of RSPO1 are known to exist.
Specifications

Specifications

RSPO1
Monoclonal
Unconjugated
RSPO1
Lyophilized
RSPO1
Human recombit protein fragment corresponding to amino acids 21-263 of human RSPO1 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
OTI1C3
PBS with 8% trehalose and no preservative; pH 7.3
Q2MKA7
CRISTIN3, RSPO
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
284654
SDS
Documents
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