Invitrogen™ RSPO4 Monoclonal Antibody (435203)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA524160

Catalog No. PIMA524160

Description

In Western blots, 50-100% cross-reactivity with recombinant human (rh) R-Spondin 4 is observed and no cross-reactivity with recombinant mouse (rm) R-Spondin 1, rmR-Spondin 3, or rhR-Spondin 2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

RSPO4 is a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: RSPO4
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8BJ73
• Gene Symbols: RSPO4
• Immunogen: E. coli-derived recombinant mouse R-Spondin 4 Tyr21-Pro197.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 435203
• Conjugate: Unconjugated
• Gene: RSPO4
• Gene Alias: A730099F22; A930029K19Rik; C20orf182; CRISTIN4; Cristin-4; Cysteine-rich and single thrombospondin domain-containing protein 4; hRspo4; mCristin-4; roof plate-specific spondin-4; RSPO4; R-spondin 4; R-spondin family, member 4; R-spondin-4; R-spondin-like protein
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 228770
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized