Invitrogen™ RSV Fusion Protein Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522825

Catalog No. PIPA522825

Description

This antibody is reactive against Human Respiratory Syncytial Virus (RSV) and Bovine Respiratory Syncytial Virus (BRSV). Immunogen sequence: FPSDEFC.

Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps. Its genome consists of single stranded, negative sense RNA that encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. Its name comes from the fact that F proteins on the surface of the virus cause the membranes on nearby cells to merge, forming syncytia. While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.

Specifications

• Antigen: RSV Fusion Protein
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: human respiratory syncytial virus; RSV; RSV Fusion protein; Rsvgp08
• Immunogen: Residues 483-488 of the 63 kDa RSV and BRSV F protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov