Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. Invitrogen™ RT1.Ac Monoclonal Antibody (OX-27)

Invitrogen™ RT1.Ac Monoclonal Antibody (OX-27)
GREENER_CHOICE

Catalog No. PIMA170014
Change view
Click to view available options
Quantity:
250 μg
500 μg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA170014 250 μg
PIMA517463 500 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. PIMA170014 Supplier Invitrogen™ Supplier No. MA170014
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

anti-rat RT1.Ac recognizes a polymorphic determinant of the MHC class I antigen in the rat ('c' and 'n' haplotypes). This antibody is an excellent antibody for labelling cells of donor or host origin in bone marrow chimeras. Applications include flow cytometry, immunoprecipitation, and immunohistochemistry using cryostat sections (however, cross-reactivity with Lewis rats have been shown to occur in some instances).

RT1.Ac is a gene located within the major histocompatibility complex (MHC) region of the rat genome and is a part of the class I MHC genes. The MHC genes are involved in the immune response by presenting peptide antigens to T cells, enabling the immune system to recognize and respond to pathogens. RT1.Ac encodes for a protein that is a homolog to human HLA and mouse H2 class I molecules, playing a crucial role in the activation and regulation of immune responses. This gene's expression on the surface of cells allows for the presentation of endogenous peptides to cytotoxic T lymphocytes, facilitating the detection and destruction of infected or malignantly transformed cells. Researchers often use RT1.Ac in studies involving transplantation immunology and autoimmune disease models, due to its pivotal role in antigen presentation and immune recognition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RT1.Ac
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Classification Monoclonal
Clone OX-27
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Alias RT1-Ac
Host Species Mouse
Immunogen Phytohaemagglutinin Blasts.
Purification Method Protein G
Quantity 250 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.