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Invitrogen™ RT1.D Monoclonal Antibody (OX-17), PE
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Catalog No. PIMA517439
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50 μg
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PIMA517439 50 μg
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Catalog No. PIMA517439 Supplier Invitrogen™ Supplier No. MA517439
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Description

Mouse Monoclonal Antibody

MA5-17439 targets RT1.D in FACS applications and shows reactivity with Rat samples. The MA5-17439 immunogen is rat spleen membrane glycoproteins depleted of Ia-A antigens.

RT1.D is a gene located within the major histocompatibility complex (MHC) region of the rat genome, specifically part of the RT1 complex. RT1.D, along with its counterpart RT1.B, comprises class II MHC genes, which are key players in the adaptive immune response. These genes encode for proteins that present extracellularly derived peptides to helper T cells (CD4+ T cells), facilitating the activation and regulation of immune responses. The RT1.D gene product is analogous to human HLA-DR and mouse I-A/I-E molecules, playing an essential role in antigen presentation and immune recognition. RT1.D genes are highly polymorphic, which influences susceptibility to various diseases and are often utilized in studies involving autoimmune diseases, immune response, and transplantation immunology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RT1.D
Applications Flow Cytometry
Classification Monoclonal
Clone OX-17
Concentration 0.1 mg/mL
Conjugate PE
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene RT1-Db1
Gene Accession No. P18211
Gene Alias Db1; MHC class II RT1D beta1 chain antigen; rano class II histocompatibility antigen, D-1 beta chain; rat class I D; RT1 class II histocompatibility antigen, D-1 beta chain; RT1 class II, locus Db1; RT1-D beta; RT1-Db; RT1-Db1; RT1-Db1n
Gene Symbols RT1-Db1
Host Species Mouse
Immunogen Rat spleen membrane glycoproteins depleted of Ia-A antigens.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 294270
Target Species Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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