RTKN Monoclonal Antibody (OTI2E9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA505104

Catalog No. 50-167-5652

Description

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: RTKN
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9BST9
• Gene Symbols: RTKN
• Immunogen: Full length human recombit protein of human RTKN produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2E9
• Conjugate: Unconjugated
• Gene: RTKN
• Gene Alias: rhotekin
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6242
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid