RTKN Monoclonal Antibody (OTI2E9), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-5652	100 μL
50-253-9913	30 μL

Catalog No. 50-167-5652 Supplier OriGene Supplier No. TA505104

Description

Mouse Monoclonal Antibody

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: RTKN
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2E9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: RTKN
• Gene Accession No.: Q9BST9
• Gene Alias: rhotekin
• Gene Symbols: RTKN
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human RTKN produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6242
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a