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RTKN Monoclonal Antibody (OTI2E9), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA505104

Encompass_Preferred

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Catalog No. 50-167-5652


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Description

Description

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications

Specifications

RTKN
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9BST9
RTKN
Full length human recombit protein of human RTKN produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG2a
Immunohistochemistry (Paraffin), Western Blot
OTI2E9
Unconjugated
RTKN
rhotekin
Mouse
Affinity Chromatography
RUO
6242
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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