RTKN Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8231	Proteintech Group Inc 127621AP150UL	150 μL

Description

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: RTKN
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q6V7V2, Q8C6B2, Q9BST9
• Gene ID (Entrez): 20166, 297383, 6242
• Immunogen: RTKN Fusion Protein Ag3265
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: RTKN

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: rhotekin, RTKN, RTKN1
• Gene Symbols: RTKN
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody