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  6. RU 28318, potassium salt, Tocris Bioscience™

RU 28318, potassium salt, Tocris Bioscience™

Catalog No. 167250
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Catalog No. Quantity
16-725-0 50 mg
16-721-0 10 mg
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Catalog No. 16-725-0 Supplier R&D Systems Supplier No. 1672/50
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Description

Potent, selective mineralocorticoid receptor antagonist

Potent and selective antagonist for the mineralocorticoid receptor (MR). Inhibits aldosterone production and secretion, and selectively decreases ex-vivo MR binding in the hippocampus of adrenalectomised rats. Also decreases blood pressure in female rats following central administration in vivo.

Chemical Identifiers

CAS 76676-34-1
Molecular Formula C25H37KO4
Molecular Weight (g/mol) 440.665
InChI Key HXJITUGMCJCKCE-UYOQDFFISA-M
Synonym 7a,17a-17-hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid, potassium salt
PubChem CID 23677972
IUPAC Name potassium;3-[(7R,8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-7-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
SMILES CCCC1CC2=CC(=O)CCC2(C3C1C4CCC(C4(CC3)C)(CCC(=O)[O-])O)C.[K+]

Specifications

Quantity 50 mg
Formula Weight 440.66
Percent Purity >98%
Chemical Name or Material RU 28318, potassium salt

Safety and Handling

Recommended Storage Desiccate at +4°C
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