Invitrogen™ RUNX1/RUNX2/RUNX3 Recombinant Rabbit Monoclonal Antibody (6G5U2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535649

Catalog No. PIMA535649

Description

Immunogen sequence: LPPPYPGSSQ AQGGPFQASS PSYHLYYGAS AGSYQFSMVG GERSPPRILP PCTNASTGSA LLNPSLPNQS DVVEAEGSHS NSPTNMAPSA RLEEAVWRPY.

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are welldocumented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: RUNX1/RUNX2/RUNX3
• Classification: Recombinant Monoclonal
• Concentration: 0.28 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q01196, Q03347, Q08775, Q13761, Q13950, Q64131
• Gene Symbols: RUNX1, Runx2, RUNX3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 354-453 of human RUNX1/2/3 (NP_0010018901).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 6G5U2
• Conjugate: Unconjugated
• Gene: RUNX3
• Gene Alias: acute myeloid leukemia 1 protein; Acute myeloid leukemia 2 protein; acute myeloid leukemia 3 protein; acute myeloid leukemia gene 2; AKV core binding factor; AML1; AML1-EVI-1; AML1-EVI-1 fusion protein; AML2; Aml3; AMLCR1; Cbf; CBF2alpha; Cbfa1; Cbfa-1; CBFA2; Cbfa3; CBF-alpha-1; CBF-alpha-2; CBF-alpha-3; CCD; CCD1; CLCD; core binding factor alpha 1; core binding factor alpha 2; core binding factor alpha 3; core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene); core-binding factor subunit alpha-1; Core-binding factor subunit alpha-2; core-binding factor subunit alpha-3; core-binding factor, runt domain, alpha subunit 1; core-binding factor, runt domain, alpha subunit 2; core-binding factor, runt domain, alpha subunit 3; EVI-1; LS3; oncogene AML-1; Oncogene AML-2; oncogene AML-3; OSF2; OSF-2; Osteoblast-specific transcription factor 2; PEA2 alpha C; PEA2aA; PEA2-alpha A; PEA2-alpha B; PEA2-alpha C; PEBP2 alpha A; PEBP2 alpha C; Pebp2a; Pebp2a1; Pebp2a2; Pebp2a3; PEBP2aA; PEBP2aB; PEBP2aC; PEBP2alpha; PEBP2-alpha A; PEBP2-alpha B; PEBP2-alpha C; Pebpa2a; Pebpa2b; Polyomavirus enhancer-binding protein 2 alpha A subunit; polyomavirus enhancer-binding protein 2 alpha B subunit; Polyomavirus enhancer-binding protein 2 alpha C subunit; runt domain, alpha subunit 1; runt domain, alpha subunit 2; runt domain, alpha subunit 3; runt related transcription factor 1; runt related transcription factor 2; runt related transcription factor 3; runt-related transcription factor 1; Runt-related transcription factor 2; runt-related transcription factor 3; RUNX 2; Runx1; RUNX1/ZNF687 fusion; Runx2; RUNX-2; RUNX3; SL3/AKV core-binding factor alpha A subunit; SL3/AKV core-binding factor alpha B subunit; SL3/AKV core-binding factor alpha C subunit; SL3-3 enhancer factor 1 alpha A subunit; SL3-3 enhancer factor 1 alpha B subunit; SL3-3 enhancer factor 1 alpha C subunit; transcription factor; transcription factor AML2; transcription factor AML2/CBFA3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12393, 12394, 12399, 860, 861, 864
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid