RUNX3 Mouse anti-Human, Clone: OTI12F2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF810566

Catalog No. 50-167-0171

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5′-PYGPYGGT-3′ found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: RUNX3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RUNX3
• Gene Alias: AML2, CBFA3, PEBP2aC
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 864
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI12F2
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q13761
• Gene Symbols: RUNX3
• Immunogen: Full length human recombit protein of human RUNX3 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b