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RuvBL2 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
$151.31 - $568.26
Specifications
| Antigen | RuvBL2 |
|---|---|
| Applications | Immunohistochemistry |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Form | Liquid |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-157-2564
|
Bethyl Laboratories, Inc
IHC00701T |
10 μL |
Each for $151.31
|
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50-157-2563
|
Bethyl Laboratories, Inc
IHC00701 |
100 μL |
Each for $568.26
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Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla,
Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL2 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. May also inhibit the transcriptional activity of ATF2.Specifications
| RuvBL2 | |
| Polyclonal | |
| Liquid | |
| RUO | |
| TBS with 0.1% BSA and 0.09% sodium azide | |
| CGI-46, ECP51, RVB2, TIP48, TIP49B | |
| Between 1 and 50 | |
| Primary | |
| 4° C | |
| RUVBL2 |
| Immunohistochemistry | |
| Unconjugated | |
| Rabbit | |
| Human, Mouse | |
| Q9WTM5, Q9Y230 | |
| 10856, 20174 | |
| IgG | |
| Antigen affinity chromatography | |
| Antibody |
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