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RWJ 56110, Tocris Bioscience™

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Quantity:
1 mg
This item is not returnable. View return policy
2387505-58-8
C41H45Cl4F2N7O3
863.65
MGZSVSHDIOPSBO-ZEUUMAKDSA-N
?s-n-1s-3-amino-1-phenylmethyl amino carbonyl propyl-?-1-2,6-dichlorophenyl methyl-3-1-pyrrolidinylmethyl-1h-indol-6-yl amino carbonyl amino-3,4-difluoro-benzenepropanamide
90488773
(2S)-4-amino-N-benzyl-2-[(2S)-2-[({1-[(2,6-dichlorophenyl)methyl]-3-[(pyrrolidin-1-yl)methyl]-1H-indol-6-yl}carbamoyl)amino]-3-(3,4-difluorophenyl)propanamido]butanamide dihydrochloride
Cl.Cl.NCC[C@H](NC(=O)[C@H](CC1=CC(F)=C(F)C=C1)NC(=O)NC1=CC=C2C(CN3CCCC3)=CN(CC3=C(Cl)C=CC=C3Cl)C2=C1)C(=O)NCC1=CC=CC=C1
This item is not returnable. View return policy
2387505-58-8
C41H45Cl4F2N7O3
863.65
MGZSVSHDIOPSBO-ZEUUMAKDSA-N
?s-n-1s-3-amino-1-phenylmethyl amino carbonyl propyl-?-1-2,6-dichlorophenyl methyl-3-1-pyrrolidinylmethyl-1h-indol-6-yl amino carbonyl amino-3,4-difluoro-benzenepropanamide
90488773
(2S)-4-amino-N-benzyl-2-[(2S)-2-[({1-[(2,6-dichlorophenyl)methyl]-3-[(pyrrolidin-1-yl)methyl]-1H-indol-6-yl}carbamoyl)amino]-3-(3,4-difluorophenyl)propanamido]butanamide dihydrochloride
Cl.Cl.NCC[C@H](NC(=O)[C@H](CC1=CC(F)=C(F)C=C1)NC(=O)NC1=CC=C2C(CN3CCCC3)=CN(CC3=C(Cl)C=CC=C3Cl)C2=C1)C(=O)NCC1=CC=CC=C1

Description

Selective PAR1 antagonist

Selective protease-activated receptor-1 (PAR1) antagonist; displays no activity at PAR2, PAR3, or PAR4 subtypes. Blocks thrombin-induced platelet aggregation and activation of MAPK in HUVECs. Also inhibits angiogenesis in a chick embryo angiogenesis model in vivo.
Quantity 1 mg
Formula Weight 863.65
Percent Purity >96%
Chemical Name or Material RWJ 56110

Safety and Handling

Recommended Storage : Store at -20°C

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