RXR-gamma Mouse anti-Human, Clone: 12RX-2D3, Active Motif™

Catalog No.	Quantity
50-199-3085	100 μg

Catalog No. 50-199-3085 Supplier Active Motif Supplier No. 61033

Description

Mouse Monoclonal Antibody

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Specifications

• Antigen: RXR-gamma
• Applications: Gel Shift, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 12RX-2D3
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene: RXRG
• Gene Accession No.: P48443
• Gene Alias: Nr2b3; Nuclear receptor subfamily 2 group B member 3; Retinoic acid receptor RXR-gamma; retinoic X receptor gamma-1; retinoid X receptor; Retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma; RXR gamma-1; RXRC; Rxrg
• Gene Symbols: RXRG
• Host Species: Mouse
• Immunogen: This RXR-gamma antibody was raised against a peptide within the D-region of mouse RXR-gamma.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6258
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG