RXR-gamma Mouse anti-Human, Clone: 12RX-2D3, Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 61033

Catalog No. 50-199-3085

Description

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Specifications

• Antigen: RXR-gamma
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: P48443
• Gene Symbols: RXRG
• Immunogen: This RXR-gamma antibody was raised against a peptide within the D-region of mouse RXR-gamma.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Gel Shift, Immunohistochemistry, Western Blot
• Clone: 12RX-2D3
• Conjugate: Unconjugated
• Gene: RXRG
• Gene Alias: Nr2b3; Nuclear receptor subfamily 2 group B member 3; Retinoic acid receptor RXR-gamma; retinoic X receptor gamma-1; retinoid X receptor; Retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma; RXR gamma-1; RXRC; Rxrg
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6258
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid