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Invitrogen™ RXRA Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA19096
Description
This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
Specifications
RXRA | |
Polyclonal | |
Unconjugated | |
Rxra | |
9530071D11Rik; Nr2b1; Nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; retinoid X receptor; retinoid X receptor alpha; retinoid X receptor, alpha; rxr alpha; RXR alpha 1; Rxra; RXRalpha1 | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
6256 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Flow Cytometry, Western Blot, Immunocytochemistry | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
P19793 | |
Rxra | |
Internal sequence corresponding to amino acids CQVNSSLTSPTGRGSM (aa 14-28). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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