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Invitrogen™ RXRA Polyclonal Antibody
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Catalog No. PIPA585395
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100 μL
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PIPA585395 100 μL
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Catalog No. PIPA585395 Supplier Invitrogen™ Supplier No. PA585395
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (99%), Rat (99%), Bovine (97%). Positive Control: HepG2, rat liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RXRA
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Rxra
Gene Accession No. P19793, Q05343
Gene Alias 9530071D11Rik; Nr2b1; Nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; retinoid X receptor; retinoid X receptor alpha; retinoid X receptor, alpha; rxr alpha; RXR alpha 1; Rxra; RXRalpha1
Gene Symbols Rxra
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Retinoid X Receptor alpha. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25271, 6256
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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