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Invitrogen™ RXRA Recombinant Rabbit Monoclonal Antibody (JG99-38)
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Catalog No. PIMA534806
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100 μL
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PIMA534806 100 μL
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Catalog No. PIMA534806 Supplier Invitrogen™ Supplier No. MA534806
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Rabbit Recombinant Monoclonal Antibody

Positive Control: MCF-7, rat liver tissue, human esophagus tissue.

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RXRA
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JG99-38
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Rxra
Gene Accession No. P19793
Gene Alias 9530071D11Rik; Nr2b1; Nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; retinoid X receptor; retinoid X receptor alpha; retinoid X receptor, alpha; rxr alpha; RXR alpha 1; Rxra; RXRalpha1
Gene Symbols Rxra
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Retinoid X Receptor alpha aa 1-50.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6256
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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