Invitrogen™ RXRB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1815

Catalog No. PA1815

Description

PA1-815 detects retinoid X receptor (RXR) beta from human and mouse cells as well as transfected human and mouse RXR beta. PA1-815 has been successfully used in Western blot, immunoprecipitation and gel shift procedures. By Western blot, this antibody detects an ~50 kDa protein representing RXR beta from COS cells transfected with the human gene. Gel shift assays reveal supershifting of vitamin D receptor (VDR)/RXR beta/vitamin D receptor response element (VDRE) complexes when PA1-815 is preincubated with RXR beta prior to addition of VDR. The PA1-815 immunogen is a synthetic peptide corresponding to residues Q(190) K S D Q G V E G P G A T(202) of mouse RXR beta. Recombinant human VDR (Cat. # RP-710) and human RXR beta (catalog # RP-812) proteins can be purchased separately for control experiments in Western blot, immunoprecipitation and gel shift procedures.

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.

Specifications

• Antigen: RXRB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rxrb
• Gene Alias: AL023085; DADB-100D22.1; DAUDI6; H-2RIIBP; MGC1831; MHC class I promoter binding protein; MHC class I regulatory element-binding protein H-2RIIBP; NR2B2; nuclear receptor coregulator 1; nuclear receptor co-regulator 1; nuclear receptor subfamily 2 group B member 2; putative retinoid X receptor beta; RCoR-1; Retinoic acid receptor RXR-beta; retinoic acid receptor, beta; retinoid X receptor; retinoid X receptor beta; retinoid X receptor, beta; Rub; RXR Beta; Rxrb; RXR-beta
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Gel Shift, Immunoprecipitation, Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.05% sodium azide
• Gene Accession No.: P28702, P28704
• Gene Symbols: Rxrb
• Immunogen: Synthetic peptide corresponding to residues Q(190) K S D Q G V E G P G A T(202) of mouse RXR beta.
• Regulatory Status: RUO
• Gene ID (Entrez): 20182, 6257
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid