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Invitrogen™ RXRG Monoclonal Antibody (1373)
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Catalog No. MA14671
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100 μL
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MA14671 100 μL
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Catalog No. MA14671 Supplier Invitrogen™ Supplier No. MA14671
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Description

Mouse Monoclonal Antibody

This antibody is predicted to react with bovine, mouse and non-human primate based on 100% sequence homology. This antibody is specific for the ~48 kDa RXR-gamma protein.

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
TRUSTED_SUSTAINABILITY

Specifications

Antigen RXRG
Applications Western Blot
Classification Monoclonal
Clone 1373
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene RXRG
Gene Accession No. P48443, Q5BJR8
Gene Alias Nr2b3; Nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma; retinoic X receptor gamma-1; retinoid X receptor; retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma; RXR gamma-1; RXRC; RXRG
Gene Symbols RXRG
Host Species Mouse
Immunogen Synthetic peptide corresponding to the hinge region of human RXRG conjugated to KLH.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6258, 83574
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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