Invitrogen™ RXRG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581256

Catalog No. PIPA581256

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human RXRG.

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Specifications

• Antigen: RXRG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RXRG
• Gene Alias: Nr2b3; Nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma; retinoic X receptor gamma-1; retinoid X receptor; retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma; RXR gamma-1; RXRC; RXRG
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6258
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P48443
• Gene Symbols: RXRG
• Immunogen: A synthetic peptide corresponding to the center region of the Human RXRG.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG