Invitrogen™ RXRG Polyclonal Antibody

Catalog No.	Quantity
PIPA599712	100 μL

Catalog No. PIPA599712 Supplier Invitrogen™ Supplier No. PA599712

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RXR gamma.

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Specifications

• Antigen: RXRG
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: RXRG
• Gene Accession No.: P48443, Q5BJR8
• Gene Alias: Nr2b3; Nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma; retinoic X receptor gamma-1; retinoid X receptor; retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma; RXR gamma-1; RXRC; RXRG
• Gene Symbols: RXRG
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human RXRG(Accession P48443), corresponding to amino acid residues D180-G230.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6258, 83574
• Target Species: Human, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov