Invitrogen™ RYK Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5111217	Invitrogen™ PA5111217	100 μL
PIPA5111731	Invitrogen™ PA5111731	100 μL

Description

Immunogen sequence: SMKRIELDDS ISASSSSQGL SQPSTQTTQY LRADTPNNAT PITSSLGYPT LRIEKNDLRS VTLLEAKGKV KDIAISRERI TLKDVLQEGT FGRIFHGILI DEKDPNKEKQ AFVKTVKDQA SEIQVTMMLT ESCKLRGLHH RNLLPITH.

RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.

Specifications

• Antigen: RYK
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P34925
• Gene ID (Entrez): 6259
• Immunogen: Recombinant Protein corresonding to Human RYK. Recombinant protein control fragment (Product #RP-102981).
• Product Type: Antibody

• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: RYK
• Gene Alias: AW536699; D3S3195; ERK3; ERK-3; growth factor receptor; hydroxyaryl-protein kinase; JTK5; JTK5A; JTK5A protein tyrosine kinase; kinase VIK; Met-related kinase; Mrk; NYK-R; receptor-like tyrosine kinase; RYK; RYK1; tyrosine-protein kinase RYK; Vik
• Gene Symbols: RYK
• Primary or Secondary: Primary
• Purification Method: Antigen Affinity Chromatography