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Invitrogen™ RyR1 Monoclonal Antibody (G-1)
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Catalog No. MA183782
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50 μg
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MA183782 50 μg
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Catalog No. MA183782 Supplier Invitrogen™ Supplier No. MA183782
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Description

Mouse Monoclonal Antibody

For immunofluorescent applications, visualization by confocal microscopy is required. Detection by standard fluorescent microscopy will not be adequate to detect the RyR. Additionally, fluorescent, and not enzymatic, detection is required. Due to the intensity of confocal lasers, the use of an anti-fading agent such as DABCO is strongly recommended. Mouse anti Human Ryanodine Receptor antibody, clone RYR-1 recognizes the human ryanodine receptor 1, also known as Skeletal muscle calcium release channel or skeletal muscle ryanodine receptor.

Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscled cells. Ryanodine receptor, ~500 kDa, can be isolated from a variety of cell types such as lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscles, cardiac muscle and brain tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RyR1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone G-1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.01% sodium azide
Gene RYR1
Gene Accession No. E9PZQ0, F1LMY4, P16960, P21817
Gene Alias AI528790; calcium release channel; calcium release channel (ryanodine receptor 1); calcium release channel protein; CCO; central core disease of muscle; CRC; CRC1, RYR1; halothane; LOW QUALITY PROTEIN: ryanodine receptor 1; MHS; MHS1; porcine stress syndrome; PPP1R137; protein phosphatase 1, regulatory subunit 137; ryanodine receptor; ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like, skeletal muscle; RYDR; Ryr; Ryr1; RYR-1; Ryr1l; sarcoplasmic reticulum calcium release channel; skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; skrr; type 1 ryanodine receptor; type 1-like ryanodine receptor; unnamed protein product
Gene Symbols RYR1
Host Species Mouse
Immunogen Short synthetic polypeptide corresponding to the C-terminal domain of the ryanodine receptor.
Purification Method Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100139857, 114207, 20190, 396718, 606491, 6261
Target Species Human, Mouse, Rat, Canine, Bovine, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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