Invitrogen™ RyR1 Monoclonal Antibody (G-1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA183782

Catalog No. MA183782

Description

For immunofluorescent applications, visualization by confocal microscopy is required. Detection by standard fluorescent microscopy will not be adequate to detect the RyR. Additionally, fluorescent, and not enzymatic, detection is required. Due to the intensity of confocal lasers, the use of an anti-fading agent such as DABCO is strongly recommended. Mouse anti Human Ryanodine Receptor antibody, clone RYR-1 recognizes the human ryanodine receptor 1, also known as Skeletal muscle calcium release channel or skeletal muscle ryanodine receptor.

Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscled cells. Ryanodine receptor, ~500 kDa, can be isolated from a variety of cell types such as lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscles, cardiac muscle and brain tissues.

Specifications

• Antigen: RyR1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.01% sodium azide
• Gene Accession No.: E9PZQ0, F1LMY4, P16960, P21817
• Gene Symbols: RYR1
• Immunogen: Short synthetic polypeptide corresponding to the C-terminal domain of the ryanodine receptor.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Bovine, Pig
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Clone: G-1
• Conjugate: Unconjugated
• Gene: RYR1
• Gene Alias: AI528790; calcium release channel; calcium release channel (ryanodine receptor 1); calcium release channel protein; CCO; central core disease of muscle; CRC; CRC1, RYR1; halothane; LOW QUALITY PROTEIN: ryanodine receptor 1; MHS; MHS1; porcine stress syndrome; PPP1R137; protein phosphatase 1, regulatory subunit 137; ryanodine receptor; ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like, skeletal muscle; RYDR; Ryr; Ryr1; RYR-1; Ryr1l; sarcoplasmic reticulum calcium release channel; skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; skrr; type 1 ryanodine receptor; type 1-like ryanodine receptor; unnamed protein product
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 100139857, 114207, 20190, 396718, 606491, 6261
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov