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Ryuvidine, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
265312-55-8
C15H12N2O2S
284.333
HFPLHASLIOXVGS-UHFFFAOYSA-N
cdk4 inhibitor iii, ryuvidine, 2-methyl-5-4-methylphenyl amino benzothiazole-4,7-dione, 5-n-4-methylphenyl amino-2-methyl-4,7-dioxobenzothiazole, 2-methyl-5-p-tolylamino-benzothiazole-4,7-dione, 2-methyl-5-4-methylanilino-1,3-benzothiazole-4,7-dione, d07hpe, 2-methyl-5-4-methylphenyl amino-4,7-benzothiazoledione, 2-methyl-5-p-tolylamino benzo d thiazole-4,7-dione, 2-methyl-5-4-methylphenylamino-4,7-dihydrobenzothiazole-4,7-dione
481747
2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione
CC1=CC=C(C=C1)NC2=CC(=O)C3=C(C2=O)N=C(S3)C
This item is not returnable. View return policy
265312-55-8
C15H12N2O2S
284.333
HFPLHASLIOXVGS-UHFFFAOYSA-N
cdk4 inhibitor iii, ryuvidine, 2-methyl-5-4-methylphenyl amino benzothiazole-4,7-dione, 5-n-4-methylphenyl amino-2-methyl-4,7-dioxobenzothiazole, 2-methyl-5-p-tolylamino-benzothiazole-4,7-dione, 2-methyl-5-4-methylanilino-1,3-benzothiazole-4,7-dione, d07hpe, 2-methyl-5-4-methylphenyl amino-4,7-benzothiazoledione, 2-methyl-5-p-tolylamino benzo d thiazole-4,7-dione, 2-methyl-5-4-methylphenylamino-4,7-dihydrobenzothiazole-4,7-dione
481747
2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione
CC1=CC=C(C=C1)NC2=CC(=O)C3=C(C2=O)N=C(S3)C

Description

SETD8 inhibitor; also CDK4 inhibitor

Inhibitor of SETD8 protein lysine methyltransferase (PKMT) (IC50 = 0.5 μM); suppresses H4K20 monomethylation in vitro. Also inhibits cyclin-dependent kinase (CDK) 4 (IC50 = 6.0 μM at CDK4/cyclin D1). Induces S phase accumulation in HEK293T cells. Cytotoxic against a range of human cancer cells.
Quantity 10 mg
Formula Weight 284.33
Percent Purity >98%
Chemical Name or Material Ryuvidine

Safety and Handling

Recommended Storage : Store at +4°C