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  5. Tocris Bioscience™ (S)-(+)-Dimethindene maleate

Tocris Bioscience™ (S)-(+)-Dimethindene maleate
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Catalog No. 142550
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14-255-0 50 mg
14-251-0 10 mg
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Description

M2-selective antagonist

(S)-(+)-Dimethindene maleate is an enantiomer that is a subtype-selective M2 muscarinic receptor antagonist (pKi values are 7.08, 7.78, 6.70 and 7.00 for M1, M2, M3 and M4 receptors respectively). Also H1 histamine receptor antagonist (pKi = 7.48). Allows formation of extended pluripotent stem (EPS) cells in combination with CHIR 99021 (Cat.No. 4423), minocycline hydrochloride (Cat.No. 3268) and human leukemia inhibitory factor.

For more information about how Dimethindene maleate may be used, see our protocol: Generation and Propagation of EPS cells (LCDM Cocktail) .

Chemical Identifiers

CAS 136152-65-3
Molecular Formula C24H28N2O4

Specifications

Quantity 50 mg
Formula Weight 408.5
Purity >99%
Molecular Weight (g/mol) 408.498
Chemical Name or Material (S)-(+)-Dimethindene maleate

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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