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  5. Tocris Bioscience™ (S)-Duloxetine hydrochloride

Tocris Bioscience™ (S)-Duloxetine hydrochloride
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Catalog No. 479850
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Catalog No. Quantity
47-985-0 50 mg
47-981-0 10 mg
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Catalog No. 47-985-0 Supplier Tocris Bioscience™ Supplier No. 4798/50
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Description

Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake

High affinity, competitive 5-HT and noradrenaline (NA) re-uptake inhibitor (Ki values are 8.5 and 45 nM for 5-HT and NA reuptake respectively in cortical synaptosomes; IC50 values are 28 and 46 nM for 5-HT and NA reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki = 300 nM in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable.

Chemical Identifiers

CAS 136434-34-9
Molecular Formula C18H20ClNOS

Specifications

Quantity 50 mg
Formula Weight 333.88
Purity >99%
Molecular Weight (g/mol) 333.87
Chemical Name or Material (S)-Duloxetine hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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