S100 beta Mouse anti-Human, Porcine, Rat, Clone: 1G10F4, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-7034	Proteintech Group Inc 666161IG150UL	150 μL

Description

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer′s disease, Down′s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Specifications

• Antigen: S100 beta
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: NEF, Protein S100 B, S 100 protein beta chain, S 100 protein subunit beta, S100, S100 calcium binding protein B, S100B, S100beta
• Gene Symbols: S100B
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1G10F4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Pig, Rat
• Gene Accession No.: P04271, P04631
• Gene ID (Entrez): 100623510, 25742, 6285
• Immunogen: S100 beta Fusion Protein Ag7440
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: S100B